BIOPHYISCAL AND BIOCHEMICAL PROCESSES ON SUBSTRATES:

MICROARRAYS AND MEMBRANES STUDIED BY LABEL-FREE OPTICAL MICROSCOPES

"Label-free screening small-molecule compound libraries for protein ligands using a high-throughput optical scanning microscope," with Y.Y. Fei, J.P. Landry, Y.S. Sun, J.T. Luo, X.B. Wang, C.Y. Wu, and K.S. Lam, Proc. of SPIE 7182, 7182Q2 (2009).

"Label-free optical detection of small-molecule compound microarray immobilized on solid support using macromolecular scaffolds and subsequent protein binding reactions," with Y.S. Sun, J.P. Landry, Y.Y. Fei, J.T. Luo, X.B. Wang, and K.S. Lam, Proc. of SPIE 7182, 71820P (2009).

"Macromolecular scaffolds for immobilizing small molecule microarrays in label-free detection of protein-ligand interactions on solid support (PDF)," with Y.S. Sun, J.P. Landry, Y.Y. Fei, J.T. Luo, X.B. Wang, and K.S. Lam, Anal. Chem. 81, 5373-5380 (2009).

"Effect of fluorescently labelling protein probes on kinetics of protein-ligand reactions (PDF)," with Y.S. Sun, J.P. Landry, Y.Y. Fei, J.T. Luo, X.B. Wang, and K.S. Lam, Langmuir 24, 13399-13405 (2008).

"A study of protein reactions with surface-bound molecular targets using oblqiue-incidence reflectivity difference microscope (PDF)," with J.P. Landry, Y.S. Sun, and X.W. Guo, Appl. Opt. 47, 3275-3288 (2008).

"A novel high-throughput scanning microscope for label-free detection of protein and small-molecule chemical microarrays (PDF)," with Y.Y. Fei, J.P. Landry, Y.S. Sun, J.T. Luo, X.B. Wang, K.S. Lam, Rev. Sci. Instrum. 79, 013708 (2008).

"Oblique-Incidence Reflectivity Difference Microscope for Label-Free High-Throughput Detection of Biochemical Reactions in Microarray Format (PDF)," with J.P. Landry, Y.S. Sun, J.P. Gregg, and K.S. Lam, Appl. Opt. 46, 1890 (2007).

"Biophotonic studies on lipid membranes using oblique-incidence reflectivity difference (OI-RD) ellipsometry," with R. Masina, A.N. Parikh, R. Bruch, and J.P. Landry, Proc. SPIE. 6095, 153-161 (2006).

"Applications of Oblique-Incidence Reflectivity Difference Method in Primary Study of Protein Biomolecules (PDF)," with H.Y. Zhang, R.Q. Liang, K.J. Jin, H.B. Lu, X.D. Zhu, Y.L. Zhou, K.C. Ruan, and G.Z. Yang, Chin. Phys. Lett. 23, 1032 (2006).

"Incidence-angle dependence of optical reflectivity difference from an ultrathin film on solid surface (PDF)," with J.P. Landry, J.J. Gray, and M.K. O'Toole, Opt. Lett. 31, 531-533 (2006).

"Comparison of two optical techniques for label-free detection of biomolecular microarrays on solids (PDF)," Opt. Commun. 259, 751-753 (2006).

"Detection of biomolecular microarrays without fluorescent-labeling agents (PDF)," with J.P. Landry, J.P. Gregg, and X.W. Guo, Proc. of SPIE. 5328, 121 (2004).

"Label-free detection of microarrays of biomolecules using oblique-incidence reflectivity difference microscopy (PDF)," with J.P. Landry, J. Gregg, Opt. Lett.. 29, 581 (2004).

"Oblique-Incidence Reflectivity Difference and Fluorescence Imaging of Oligonucleotide and IgG Protein Microarrays," with J. P. Landry, J. Gregg, X.W. Guo, Mat. Res. Soc. Proc. 773, N5.5.1 (2003) (PDF).